Ron Mackie is understood to have been travelling to work at Cwrt Enfys nursing home when he was in collision with a van on the A4067 between Ystragynlais and Ystalyfera.
Emergency services were called at around 7.50am yesterday, but the 26-year-old was pronounced dead at the scene.
Karen Beech, home manager at Cwrt Enfys on Gorof Road, said: "To lose such a lovely member of staff is a huge blow," she said.
South Wales Police Roads Policing Unit is appealing for witnesses.
Leave your Lasting Tribute to Ron Mackie
A spokesman said: "A blue Honda motorcycle collided with a blue Ford Transit Toureno van, which resulted in the motorcyclist sustaining fatal injuries.
Call the Roads Policing Unit on 01656 869332, 101 or Crimestoppers on 0800 555111.