Sufferer joins in battle for trials of 'wonder drug'
A LLANELLI man is spearheading a fight for trials to be carried out on a "wonder drug" which could help treat people with illnesses ranging from Aids to cancer.
Multiple sclerosis sufferer Andrew Barnett, of Llangennech, and his partner, Jayne Crocker, who has ulcerative colitis, both take a drug called Naltrexone.
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The pair say the generic drug has been used with remarkable success to treat their conditions, and are now calling on the Government to help make it available to all.
However, the Assembly says it will only consider medicines appropriately licensed by the Medicines and Healthcare Products Regulatory Agency.
The drug went out of patent in 1986. It was introduced into the UK by Swansea-based physician Bob Lawrence in 2000.
The drug works by blocking endorphin receptors for a limited period of time, which then boosts them five-fold.
This stimulates the immune system to produce cells that repair the body.
Only about 200 doctors in the country currently prescribe the drug — many more are reluctant to do so, because it has not yet been approved by health chiefs.
Mr Barnett described how last year he reached a point where he could only support his weight on crutches. The 49-year-old was crawling out of the front door to get to his car, dragging his legs behind him.
But after taking the drug, there was a remarkable improvement.
Mr Barnett said: "Within four days of taking Low Dose Naltrexone (LDN), I could walk to the car with two walking sticks, and even walked down a friend's country path to visit them.
"The downward spiral ended there, in fact I seem to be improving as time goes by."
His partner Jayne, from Milford Haven, decided to use LDN for ulcerative colitis, which she has had for 25 years.
"Within the first month I was no longer in pain," she said.
"It's not a miracle drug, but it does work for a lot of people."
They say as well as being effective, the drug is cheap, costing less than £1 a day, and could save the NHS vast sums of money.
The couple have created a petition to take their fight to 10 Downing Street, and have already gathered around 3,000 signatures.
Mr Barnett, who has secondary progressive MS, said: "We urge the Government to fund a trial of LDN on the NHS.
"Because of lack of interest by drug companies, without political intervention, we will probably never see this drug trialled."
An Assembly spokesman said the National Institute for Health and Clinical Excellence had looked at the drug.
He continued: "Since there is no licensed product available for low dose administration in the UK it can only be obtained under a special manufacturing licence.
"Products of this nature are obtained on the full clinical responsibility of the prescriber, and any liability for any harmful effects caused rests with them."
He said researchers with an interest in Low Dose Naltrexone could apply for funding for specific research.
*To find out more about LDN and the petition, visit www.ldnnow.co.uk











33 Comments
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by A Barnett, Llanelli
Friday, August 07 2009, 11:09PM
“For a list of doctors who prescribe, visit ldnnow.com for an email address where you can get this information”
by DR P M WILLIAMS, SWANSEA
Wednesday, July 29 2009, 7:02PM
“IS THERE A LIST OF DOCTORS WHO CAN PRESCRIBE LDN?”
by Lucca, Windsor
Monday, July 27 2009, 10:33PM
“Too often, people come across this effective drug in seeking out a "last resort" - well after the point that they should have been taking LDN to prevent disease progression. My hope is that LDN will someday be the first line of defense for the majority of immune-mediated disorders. As an inexpensive drug with few minor side effects, it does not compare to the harsh, costly immunosuppresants & biologics that are the current physician protocol. I am taking LDN for Lupus and Sjogrens, among other overlapping auto-immune conditions, and have seen measurable symptomatic improvement that the plaquenil, steroids, immunomodulators had been unable to achieve. I was nearly incapacitated by those other drugs' side effects. And now, thanks to LDN, I get daily glimpses of a full functioning life and getting myself back.”
by Vicki Finlayson, Auburn, California
Friday, July 24 2009, 5:24AM
“I was diagnosed 2 weeks before my 40th birthday. I'll never forget how terrified I was not knowing what was going to happen. My dr prescribed Avonex, which I did for 7 yeras, then Copaxone, then rebif. I was on Morphine, Oxycottin, Norco, Tysabri, steroid infusions and a bunch of other drugs. Life was miserable and all my dr.'s could tell me was that it wasn't going to get any better. I kept asking if this was it they assured me it was. i was on disability, depressed and angry because my government had failed me. I found LDN and things changed. I'm off all the shots, off disability and back to work, and all because of a cheap, non evasive drug that works. I advocate heavy in California, did a 56 mile walk to our State capital hoping to talk to Governor Schwarzenegger, I did meet with 2 of his advisors, they didn't care about me, which was sad. The same with the Mayor of Sacramento and a Congressman of California. The only thing they care about is money and how profitable we are if we are sick. We need to stop this madness before they kill us all. The LDN community is growing and one day they will listen..............”
by JB, Swansea
Thursday, July 23 2009, 4:19PM
“Anyone based in London or who knows anyone in London please encourage them to go to Trafalgar square tomorrow at 11 am where Brian Lonsdale will be promoting the petition on the fourth Plinth. He will be distributing Flyers to explain how to sign the petition... Good Luck Brian!!!”